Hgh and Downs Syndrome
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Down’s Syndrome is a chronic condition faced by children which causes mental retardation retardation and physical signs as slanted eyes, flattened facial features, short status and tendency toward obesity. It is a wasting disease caused by chromosomal disorders. Recent studies have shown that Human Growth Hormones are quite helpful in treatment of this disease.
One of the features of Downs Syndrome is growth retardation, specially after age of 6 months, when growth starts to become growth hormone (GH) regulated. DS children have normal serum levels of GH. GH regulates the production of insulin-like growth factors (IGFs), which act as growth hormones. It is the deficit in IGF-1-like peptides which probably accounts for the growth retardation in DS. In a study when 5 growth-retarded children with DS were treated with hGH for 6 months, it was found that the growth velocity doubled and the serum IGF-1 levels were restored to normal concluding that DS children respond to hGH treatment.
Have a look at the abstract from the Department of Pediatrics, Kansai Medical University Kohri Hospital and judge the benefits of Hgh in Downs syndrome for yourself:
We administered recombinant human growth hormone (r-hGH) to a 4-year and 3-month old girl with Down syndrome who had a severe delay in motor development as well as short stature in an attempt to induce acceleration of motor development. She measured 91.5 cm (-2.61 SD) and weighed 13.4 kg. She had pervasive developmental delay without acquisition of language or the ability to sit up. There was improvement in her growth rate after r-hGH administration. She was capable of walking by herself after 5 months of r-hGH therapy. Eleven months after the initiation of treatment, the patient (5 years and 1 month) measured 97.8 cm (-2.43 SD) and weighed 15.2 kg. The protein anabolic activity of GH seems to have improved muscle strength and motor ability leading to improvement of her quality of life. This suggests that r-hGH therapy may be a beneficial treatment for children with Down syndrome.
This and many more studies have conclusively proved that Hgh treatment helps in children suffering from Downs Syndrome.
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