HGH treatment found helpful for opiate addicts
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It is difficult to regain the patience, attention span, memory and concentration of the addicts whose brain cells have been destroyed due to the abuse of opiates such as heroin, methadone and morphine.
But a new discovery from the researchers of Uppsala University stated in Sweden report in Proceedings of the National Academy of Sciences USA has brought a smile to the faces of the opiate addicts. The report that brain cells targeted for early death by continued opiate use may be salvaged by injections of synthetic human growth hormone (HGH). This is another addition to the benefits of HGH. Thus HGH can now be used to treat and prevent damage from abuse of opiates in addicts as well as patients undergoing chronic pain management.
Opiate use disrupts new cell growth (neurogenesis) in the hippocampus, a midbrain region implicated in short-term and so-called episodic memory (places, people and emotions linked to events). So just like aging, opiates block the formation of new nerve leading to less cell production and general memory decline.
Just as HGH treatment in aging patients helps in improved memory, in the same way, HGH has the power to clear the pathways in opiate addicts and get the process rolling again.
The team of researchers isolated developing nerve cells from a mouse fetus in petri dishes and bathed them in morphine for a week. Then they added synthetic growth hormone to some of the cultures. They found that the cells exposed only to morphine began to die off, but those also infused with HGH persisted and, in some cases, increased.
“If this works in humans as it works on these cells, we will be able to correct the impairment in hippocampus function due to opiate use,” Nyberg says. The team is also currently studying the effects of growth hormone injections on a patient undergoing chronic pain management who has also experienced memory impairment and improvement has been seen at least during the treatment regimen.
Frank Vocci of the National Institute on Drug Abuse in Bethesda, Md., says he would like to see research extended to include the potential of HGH to stave off drug dependence. Although, he notes, “this memory component may not be related to the addiction.”
(Adapted from: www.sciam.com)
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