How aging decreases growth hormone precursor levels?
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By now, we know that HGH is formed from specific amino acids. A steady supply of these amino acids must be present in sufficient concentrations in the pituitary for the synthesis of Human Growth Hormones to take place. Amino acids come from dietary protein that must be adequately digested, absorbed, and assimilated to release their constituent amino acids into what has been called the ‘protein pool’ of the body. Unfortunately, our ability to adequately digest, absorb and assimilate protein diminishes with age as our digestive processes in the stomach become compromised. Protein requires adequate levels of an acid called hydrochloric acid for digestion to take place in the stomach. The condition of low stomach acid, called hypochlorhydria, is very common as we get older. Hypochlorhydria is a side effect of a number of common degenerative diseases including diabetes, hypothyroidism, hepatitis, osteoporosis, and chronic autoimmune disease, and can be caused by the use of antacid drug therapy.
Hypochlorhydria causes the available ‘protein pool’ of amino acids to diminish as we age. It is not uncommon for an elderly person to have a 35% decrease in their available protein pool, which makes it harder for the body to synthesize specific hormones, including growth hormone.
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