How HGH decline affects psychological and physical well-being?
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People who produce little or no HGH as a result of pituitary tumors, disease or removal of pituitary gland often seem like doddering old people. In studies, such patients show a consistent pattern of mental and physical characteristics associated with aging. The psychological and emotional symptoms include a reduced sense of well-being, low energy, vitality, and capacity for work, and emotional liability, including mood swings, anxiety, depression, and increased social isolation. Important physical signs are increased body fat, especially around the waist, decreased muscle mass, and thin, wrinkled or prematurely aged akin.
As Silvio Inzucchi of Yale University wrote in the January issue of Hospital Practice, ‘Growth hormone deficiency is now formally recognized as a specific clinical syndrome, typified by decreased muscle mass, increased body fat, decreased exercise capacity, osteoporosis, abnormal lipid profiles, and diminished feelings of well-being.
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