How to go for completely safe and pure HGH products?
Anti aging, Body Building, Guide, HgH, Hgh Effects, HGH products, HGH: Human Growth Hormone, Review Comments (0)
Though advances in biotechnology has made it possible to produce bioidentical recombinant human growth hormone (rHGH), the truth is that the process is very time consuming and expensive. It is difficult to achieve complete safety when extracted, purified and packaged.
HGH is produced within living cells that divide and replicate in a complex broth of cell nutrients. HGH is manufactured using this living cell culture and so this process enormously more complex than the manufacture of other types of generic drugs such as diuretics and blood pressure medicines. It is technically difficult to ensure that every batch produces identical HGH molecules with the same 3-dimensional configuration in final product. It is relatively easy to get hormone activity, but extensive testing and quality control is required to safely produce a new follow-on protein biological (FOPP) such as HGH.
Purification and handling of proteins produced in cell cultures can also lead to variations in folding, unfolding, cross-linkages, and aggregates of multiple proteins hooked together as dimers and polymers. These impurities can be potentially dangerous as they can cause immune responses and allergy to HGH, potentially cross reacting against endogenously produced HGH from the pituitary gland. Proper extraction and purification are very complex and expensive. Tiny residues from the cell culture broth may contaminate the end-product.
To be completely safe, dimers, polymers, aggregates, improper folding, glycosylation, broken cross-linkages, pyrogens, and other contaminants must be strictly limited during manufacture and packaging. The HGH molecule is fragile. Freeze drying and other steps in the packaging process can alter its structure. Such abnormalities have reported to block hormone activity, and the end product may seem to work quite well, but the altered molecules may stimulate immune reactions and cause allergy and desensitization to HGH over time, with subsequent and permanent loss of hormone response in the body.
So, to safegurad yourself against, impure and contaminated HGH products make sure that you use FDA registered HGH products which are assigned an official NDC number (National Drug Code) by the FDA. Without that code, it is difficult or impossible to know if a product is pure and unadulterated. Unfortunately, the FDA has blocked compounding pharmacies from packaging HGH, even with FDA approved bulk ingredients. Buy only from a trusted source, as there are a number of counterfeit products being marketed with false labeling that look exactly like trusted brands, some from overseas. Also, because the FDA will not allow compounding pharmacists to package HGH, even using approved bulk ingredients, reliable sources remain with major pharmaceutical companies.
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