Human Growth Hormones - Glossary and related terms
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Going through our blog, you must have come across several terms related to Human Growth Hormones which sent your head whirling round. So, here we are always seeking your best interest with a glossary of different terms generally associated with HGH:
Hormone:
Hormones are a naturally occurring substance secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
Growth hormone:
These are Polypeptide (191 amino acids) produced by anterior pituitary that stimulates liver to produce somatomedins 1 and 2.
Human growth hormone:
Also called Somatropin, HGH is a protein produced in the pituitary gland that stimulates the liver to produce somatomedins, which stimulate growth of bone and muscle. Many researchers believe that is has greater capacity to prevent and reverse aging than any other substance.
Amino acids:
Organic compounds that generally contain an amino (-nh2) and a carboxyl (-cooh) group.
Twenty alpha-amino acids are the subunits which are polymerised to form proteins.
Amino group:
An -NH2 group. Organic compounds which have this group are called amines.
Homeopathy:
Homeopathy is a non-toxic system of medicine used to treat illness and relieve discomfort of a wide variety of health conditions. It is a system of medical practice that treats a disease especially by the administration of minute doses of a remedy that would in healthy persons produce symptoms similar to those of the disease.
IGF - Insulin like Growth Factor:
Insulin like growth factors I and II are polypeptides with considerable sequence similarity to insulin.
They are capable of eliciting the same biological responses, including mitogenesis in cell culture. On the cell surface, there are two types of insulin like growth factor receptor, one of which closely resembles the insulin receptor (which is also present).
Insulin like growth factor I = somatomedin A = somatomedin C
Insulin like growth factor II = MSA (Multiplication stimulating activity).
Insulin like growth factor 1 is released from the liver in response to growth hormone.
Acronym: IGF
Precursors:
Precurser means something which. In biological processes it means, a substance from which another, usually more active or mature substance is formed.
Pituitary gland:
An endocrine gland located at the base of the brain, in the small recess of a bone. This gland secretes important hormones including growth hormone (GH) and antidiuretic hormone (ADH).
Polypeptide:
A peptide which on hydrolysis yields more than two amino acids, called tripeptides, tetrapeptides, etc. According to the number of amino acids contained.
Secretagogue:
Substance that induces secretion from cells, originally applied to peptides inducing gastric and pancreatic secretion.
Somatotropin:
Somatotrophin is the term used for the growth hormone produced natively in animals. This growth hormone is made up of four helices containing 21-30 amino acids each.
This is an amino acid based substance secreted by the pituitary gland that promotes cell growth and maintenance, stimulates the immune system, etc.
Somatropin:
synthetic or naturally occurring growth hormone from the human pituitary gland. It is given to children with open epiphyses for the treatment of pituitary dwarfism.
rHGH
This refers to recombinant human growth hormone (somatropin). It contains the identical amino acid sequence of human GH and is “natural sequence” GH. It is chemically identical to the growth hormone produced by the pituitary gland.
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