The making of HGH in our body
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Hgh is made by the pituitary gland, which is located in the center of the brain. Pituitary cells (called somatotropes) make HGH, which is also known as somatotropin- from the Greek, meaning ‘Turning towards the body’. Fifty percent of the cells of the pituitary are somatotropes, making HGH the most abundant hormone produced by the pituitary gland.
Researchers have long noticed that peak HGH production coincides with the rapid growth phase of adolescence, hence the hormone’s name. Most HGH secretion occurs in brief bursts, or pulses, which take place during the early hours of the deepest sleep. Indeed, the old adage that ‘you grow during your sleep’ appears to have a basis in fact.
HGH remains active in the bloodstream only for a few minutes, but that is long enough to stimulate its uptake to the liver where it is converted into growth factors. The most important of these is Insulin Like Growth Factor-1 (IGF-1) also known as somatomedin C. IGF-1 is directly responsible for many of the positive benefits of HGH. Most clinicians prefer to test the levels of HGH indirectly by measuring the level of IGF-1, since the level of HGH can vary widely throughout a twenty-four hour period.
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